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LC-GF

[leukemia cell-growth factor] This biochemically uncharacterized factor is produced by a murine cultured cell line (MKM-O) of endothelial origin that was established from a tumor of a BALB/C nude mouse inoculated with human hepatoma tissue fragments (Yoshimura et al, 1987).

The cells also produce an unidentified colony stimulating factor, which acts on both human and murine bone marrow-derived granulocytes and macrophage colony-forming units (see: CFU-GM). LC-GF activity is produced also by rat vascular endothelial cells.

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