kidney-expressed chemokine |
Kidney inhibitor of apoptosis |
RVDPVNFKFLSH |
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abbr. KGF (a term with multiple meanings). This biochemically uncharacterized factor was isolated from the blood plasma of heminephrectomised rats (Esbrit et al, 1991). The protein is heat- and trypsin-resistant. It stimulates the DNA synthesis in murine kidneys and kidney cell lines and also stimulates the uptake of sodium by these cells. KGF may be a renotropic protein which can play a key role in the renal compensatory growth after uninephrectomy.
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