KU-19-19 |
Ku antigen |
peg cells |
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A cancer cell line with epithelial morphology established from a male patient with metastatic renal cell carcinoma.
The conditioned medium of these cells contains significant amounts of GM-CSF, G-CSF, IL6, and IL8. As shown by RT-PCR, the cells express mRNA for GM-CSF and IL6 receptors (Tachibana et al, 2000).
The administration of IL6 and GM-CSF enhances cell-proliferation, which can be blocked by antibodies directed aginst the two factors.
For an overview of other cell lines used in research on cytokines see: Cell lines in Cytokine Research
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