Kjr |
KKA3 |
Hemopoietic Cell Adhesion Molecule |
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This chicken gene is expressed specifically in Gamma-Delta T-cells (and not in alphabeta T-cells). KK34 possesses a signal sequence and shows 19.5 % amino acid identity with human IL5 protein and lower sequence homology to other members of a family of cytokines (short-chain four-helix bundle superfamily), IL3, IL4, IL13, and GM-CSF. The authors suggest that this clone may represent the first non-mammalian IL5.
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