KH domain

also K homology domain because of its presence in heterogeneous nuclear ribonucleoprotein K (hnRNP K) hence also: hnRNP K homology domain (Gibson et al, 1993; Siomi et al, 1993).

This evolutionarily conserved protein domain of 45-55 amino acids (Gibson et al, 1993) is found in a variety of proteins that mediate transcription, and associate with heterochromatin. Some proteins contain multiple copies of the domain (Cortes and Azorin, 2000). This domain is one of the most prevalent RNA binding domains that directly contacts single-stranded RNA (Gibson et al, 1993; Valverde et al, 2008). The domain ... ... ... ...
 
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Entry last modified: August 2014