K13L peptide

This cryptic peptide fragment with the sequence KKLVAASQAALGL (Lys-Lys-Leu-Val-Ala-Ala-Ser-Gln-Ala-Ala-Leu-Gly-Leu) has been identified in human serum by Ciociola T et al (2020). The peptide is derived from the C-terminal region of human serum albumin and corresponds to albumin(597-609). (also: HSA(597-609) [Human serum albumin(597-609)]). K13L peptide is an antimicrobial peptide that shows fungicidal activity in vitro against Candida albicans, including isolates resistant to antifungal drugs currently in use. It also exhibits a significant therapeutic effect in vivo against experimental systemic candidiasis in Galleria mellonella. K13L peptide does not show toxic or genotoxic effects against ... ... ... ...
 
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Entry last modified: May 2021