K108-K133 |
K203 |
Macrophage-derived Apoptosis-Inducing RBCC protein |
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This human anaplastic thyroid cancer cell line has been obtained from tissues of a 77-year-old woman.
The cells are spindle-like and polygonal in shape. The cells are tumorigenic in nude mice. The majority of the cells express the proliferation-related Ki-67 antigen, which is used in tumor pathology to detect proliferating cells in neoplastic diseases.
The cells spontaneously secrete G-CSF and release increased amounts of G-CSF into the conditioned medium in response to TNF, IL1-alpha, and IL1-beta. The cells
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