JM4 peptide

this peptide with the sequence GCAEHCSLNENITVPDTKV (Gly-Cys-Ala-Glu-His-Cys-Ser-Leu-Asn-Glu-Asn-Ile-Thr-Val-Pro-Asp-Thr-Lys-Val) is derived from erythropoietin, corresponding to Epo(28-46). Wang B et al (2016) have reported that treatment with JM4 peptide, which has no effects on hematopoiesis, decreases the number of dead neural cells, markedly reduces the lesion size at both 3 and 8 days postinjury, and improves functional recovery following controlled cortical injury.

JM4 peptide also suppresses IL2, IL5, IL6, TNF-alpha, and IFN-gamma and limits peripheral mononuclear cell and dendritic cell ... ... ... ...
 
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Entry last modified: May 2021