Insulin-regulated membrane aminopeptidase |
insulin-related peptide 1 |
Activin beta-C |
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abbr. IRF (a term with multiple meanings).
This factor is isolated from serum-free conditioned medium of the teratoma cell line 1246-3A (Yamada and Serrero, 1988). The factor is immunologically and biochemically related to insulin and differs from insulin-like growth factors (see: IGF).
IRF binds to the insulin receptor and functions as a stimulatory autocrine growth modulator for some insulin-dependent cell lines.
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