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Ii blood group system

also: I blood group system. This blood group system consists of two structurally related poly-N-acetyllactosamine carbohydrate antigens termed I antigen and i-antigen (I(-) phenotype).

The poly-N-acetyllactosamines consist of repeating N-acetyllactosamine disaccharide units (LacNAc; Galβ1-4GlcNAc, where Gal is D-galactose and GlcNAc is N-acetyl-D-glucosamine). The i-antigen consists of linear chains, whereas the I antigen consists of branched chains. The linear i-antigen is expressed abundantly on the surface of embryonic red blood cells and on red blood cells during times of altered erythropoiesis. During the first 18 months of life the amount of i antigens on RBC ... ... ... ... ... Subscribe to continue reading! ... ...

 

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