IgG1-IF |
IgG1 secretion factor |
CIAKGNGCQPSGVQGNCCSGHCHKEPGWVAGYCK |
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abbr. IgG1-IF. This factor is produced by activated B-cells. It elevates the synthesis of IgG1 and suppresses IgG3 and IgG2b responses in murine spleen cell cultures stimulated with bacterial lipopolysaccharides (see also: Isotype switching).
The factor is identical with IgG1-enhancing factor, BSF-p1 (B-cell stimulating factor p1) and shows the same biological activities as BSF-1 (B-cell stimulating factor-1), BCGF-2 (B-cell growth factor-2) and TCGF (T-cell growth factor). The factor is identical with IL4, a name
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