ISPs |
Isracidin |
FH6 |
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[immune suppressive protein of stress] This factor of approximately 190 kDa is generated in peripheral lymph tissue of rodents, and pigs in response to restraint stress (Fan et al, 1996).
The porcine factor isolated from pig spleen (Fu et al, 2003) causes significant suppression of the proliferations of several human cell lines derived from immune cells, including U937 (macrophages), Jurkat (T-cells), P815 (mast cells). Growth of several hepatocarcinoma cell lines, Mel (erythrocytes), and fibroblasts (
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