IL-Y |
ilys-3 |
tripartite motif-containing protein 39R |
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[Ile‑Leu‑Tyr‑Met‑Pro] This anticancer peptide has been isolated from the protein hydrolysate of Cyclina sinensis, a bivalve mollusk belonging to the Veneridae family (Yu et al, 2018). Treatment of the prostate cancer cell line DU‑145 inhibits proliferation by inducing cell death by apoptosis. The peptide enhances expression of BAX, cleaved caspase‑3 and cleaved caspase‑9 and suppresses expression of BCL2.
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