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IL35-producing induced regulatory T-cells

[interleukin-35-producing induced regulatory T-cells; IL35-induced regulatory T-cells]; abbr. iTr35, IL35-iTregs. This cell type, a subset of regulatory T-cells that is phenotypically and functionally distinct from the other known induced regulatory populations, has been described by Collison et al (2010). They are obtained by treatment of naive human or mouse T-cells with IL35. IL35-producing induced regulatory T-cells mediate suppression via IL35 but not via the inhibitory cytokines IL10 or TGF-beta. Human IL35-producing induced regulatory T-cells also suppress primary ... ... ... ... ... Subscribe to continue reading! ... ...

 

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