IL18 binding protein |
IL18BPa |
Cytomegalovirus UL142 protein |
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[IL18 binding protein, interleukin-18 binding protein] Also being referred to as IGIFBP [IGIF binding protein, IFN-gamma inducing factor binding protein]. The international non-proprietary name for IL18BP is Tadekinig-alpha, which is in clinical trials for the treatment of severe psoriasis.
Aizawa et al (1999) have purified a mouse IL18 binding protein and subsequently cloned the murine and human cDNA. The human cDNA sequence encodes a protein of 194 amino acids that includes a signal sequence of 30 amino acids.
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