IL12RB |
IL12RB2 |
Aurein 3.2 |
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[IL12R-beta-1; interleukin-12 receptor-beta-1; IL12 receptor-beta-1] In the nomenclature for CD antigens IL12RB1, which is the approved gene symbol, has been given the designation CD212. Other designations for this receptor are IL12R [interleukin-12 receptor], IL12RB [IL12R-beta, interleukin-12 receptor-beta]
IL12RB1 binds IL12 with low affinity (Chua et al, 1994). The proliferation of stimulated lymphocytes in response to IL12 can be blocked by an antibody against IL12RB1. The high-affinity receptor for IL12 is a complex between IL12RB1 and another subunit,
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