IL10 family |
IL10-iTr |
hepatocyte growth factor-1/macrophage stimulating protein |
||
abbr. IL10-iTr, IL10-iTregs [interleukin-10-induced regulatory T-cells] This subtype of regulatory T-cells has been described by Groux et al (1997). They are obtained after chronic activation of both human and murine CD4(+) T-cells in the presence of IL10 and are cells with low proliferative capacity, producing high levels of IL10, low levels of IL2, and no IL4. Unlike TGF-beta-induced regulatory T-cells, which express transcription factor Foxp3 and primarily secrete TGF-beta
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |