IKDCs |
IKHQGLPQE |
GMAP |
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also referred to as Cytokine IK (IK cytokine). Approved gene symbol: IK. A cytokine of 19 kDa found in the conditioned medium of the leukemic cell line K562 and several cancer cells (Krief et al, 1994). The protein appears to be derived from a larger protein with nuclear localization, termed RED. The nucleotide sequence of the cDNA shows no homologies with known cytokines. The human IK gene maps on chromosome 2p15-p14 (Krief et al, 1994).
IK factor inhibits HLA Class 2 antigen induction by IFN-gamma and also constitutive HLA-DR expression. IK plays a
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