IGNT |
IGSF1 |
medium-field ganglion cells |
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[immunoglobulin containing and proline rich receptor-1] Sequence analysis shows that IGPR-1 is identical with CD28H [CD28 homolog] (approved gene symbol: TMIGD2 [transmembrane and immunoglobulin domain containing 2]), which plays a role in T-cell functions (see: B7-H7).
Human IGPR-1, identified by Rahimi et al (2012), is an adhesion molecule with a broad expression in epithelial cells and endothelial cells. The gene is found in vertebrates but is absent in mouse and rat genomes. IGPR-1 regulates cellular morphology, cell-cell interaction, and cell migration. It associates with several proteins containing an
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