IDR-1 |
IDR-1018 |
progesterone induced blocking factor |
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[innate defense regulator peptide 1002] This synthetic peptide with the sequence VQRWLIVWRIRKamide has been identified in a peptide library based on Bactenecins as an innate immune defense regulator, based on its substantially more potent ability to induce chemokines (CXCL1, CXCL8, CCL2, CCL7) in human peripheral blood mononuclear cells (Nijnik et al, 2010). The enhanced chemokine induction activity of the peptide in vitro correlates with stronger protective activity in vivo in the Staphylococcus aureus-invasive infection model IDR-1002 also protects against the
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