homing peptides |
homocysteine-induced gene 2 |
WAP-4-DSC domain |
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Hominicin is a heat-stable antimicrobial peptide [DmIle-Dhb-Pro-Ala-Dhb-Pro-Phe-Dhb-Pro-Ala-Ile-Thr-Glu-Ile-Dhb-Ala-Ala-Val-Ile-Ala-Dmp] with potent activity against Staphylococcus aureus ATCC 25923, methicillin-resistant Staphylococcus aureus (MRSA) ATCC 11435 and vancomycin-intermediate Staphylococcus aureus (VISA) CCARM 3501. It has been purified from culture supernatants of Staphylococcus hominis MBBL 2-9. Antibacterial activity is lost by cleavage with proteinase K, but the peptide is resistant to trypsin, alpha-chymotrypsin, pepsin and lipase.
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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