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Histamine induced suppressor factor

abbr. HSF (a term with multiple meanings). Of several suppressor factors described in the literature, expression of this particular factor by T-lymphocytes is induced by histamine. The factor inhibits lymphocyte proliferation and lymphokine production in vitro (Center et al, 1983). The factor appears to have the same biochemical characteristics as LCF [Lymphocyte chemoattractant factor] and thus would be identical with IL16.

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