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Granzyme H

This human protein, which is found in activated T-cells (Haddad et al, 1991), is a member of the family of serine proteases known as granzymes. The approved gene symbol is GZMH. Klein et al (1990) have cloned a human cDNA from IL2 activated lymphocytes. The encoded protein, termed CSP-C [cytotoxic serine protease C] is identical with granzyme H. The enzyme is expressed predominantly by NK-cells and LAK cells (MacIvor et al, 1999). Sequence analysis shows that CGL2 [cathepsin G-like-2], which is expressed by activated ... ... ... ... ... Subscribe to continue reading! ... ...

 

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