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Glia activating factor

abbr. GAF (a term with multiple meanings). Three growth factors of approximately 30 kDa, 29 kDa, and 25 kDa have been identified in the conditioned medium of a human glioma-derived cell line by Naruo et al (1993). The factors are mitogenic for rat primary glial cells. Microsequencing of each factor shows a single amino-terminal sequence. The sequence of the 30 kDa factor includes that of the 29 kDa factor. All three factors also stimulate growth of oligodendrocyte type 2 astrocyte progenitor cells, BALB/c 3T3 fibroblasts, and PC12 cells. Growth of human ... ... ... ... ... Subscribe to continue reading! ... ...

 

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