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GSD domain

[GSD domains]

[G-protein signal desensitation domain] This domain was first observed in the Caenorhabditis elegans G-protein signaling regulator, egl-10 (Koelle and Horvitz, 1996). The domain is found in a variety of proteins involved in signaling by heterotrimeric G-proteins. G-protein-coupled receptor kinases, which phosphorylate the activated receptors and thus desensitize them, also contain a copy of this domain in their N-terminus.

For information on other protein domains and sequence motifs see also the Protein domains/sequence motifs Dictionary section of this encyclopedia.

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