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GADD

[Granzyme A-activated DNase] This enzyme, which is activated by Granzyme A through release from its complex with an inhibitory protein, is identical with nm23-H1 a nucleoside diphosphate kinase implicated in suppression of tumor metastasis. This DNase is bound to a specific inhibitor from which it is released by Granzyme (Fan et al, 2003).

For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.

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