FLAME-1 |
FLamides |
Hepatitis C virus NS5A protein |
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[FADD-like anti-apoptotic molecule-3] This nuclear protein contains a death effector domain. FLAME-3 shares significant sequence (46.6 % identity) and structural homology with DEDD. FLAME-3 interacts with DEDD and FLIP (FLAME-1) but not with the other proteins with a death effector domain, FADD, caspase-8 or caspase-10. The TFIIIC102 subunit of human transcription factor TFIIIC has been identified as a protein interacting specifically with FLAME-3. The approved gene symbol is DEDD2.
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary
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