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F-36P

This non-lymphoid leukemic cell line has been established from a patient with myelodysplastic syndrome (MDS) that progressed to overt leukemia (Chiba et al, 1991). The cells are absolutely dependent on GM-CSF or IL3 for continuous growth (see also: factor-dependent cell lines). A subline, designated F-36E, can be maintained in the presence of erythropoietin alone. Both cell lines die after growth factor withdrawal and this cannot be overcome by addition of fetal calf serum.

F-36P cells express CD45, CD13, CD33, and CD34 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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