epineurium |
Epiplexus cells |
CRLM-3 |
||
this term, coined with reference to Epione-the goddess of soothing of pain, refers to a single descending neuron in each brain hemisphere of Drosophila melanogaster. These neurons are involved in the suppression of thermal nociception. Liu J et al (2023) have reported that both neurons release a nociception-suppressing neuropeptide Allatostatin-C in response to noxious heat. Epi neurons also express the heat-activated TRP channel, Painless (Pain). Thermal activation of Epi neurons and the subsequent suppression of thermal nociception depend on Pain, and the activity of these neurons promotes avoidance behaviour.
For related information of interest see also: Cell types Dictionary, Cell lines in Cytokine Research,
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