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EP153R

[African swine fever virus EP153R] This open reading frame in the genome of African swine fever virus (ASFV) encodes a nonessential protein that has been involved in the hemadsorption process induced in virus-infected cells. EP153R encodes a C-type lectin homolog. The protein partically protects infected cells against cell death by apoptosis. Increased levels of caspase-3 and cell death is observed in cells infected with a virus deletion mutant lacking the EP153R gene, we have detected, in several virus-sensitive cells (Hurtado et al, 2004).

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