EMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQC |
EML cells |
Sphingosine-1-phosphate receptor 4 |
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referred to also as EML cells. A cell line derived from murine lymphohematopoietic progenitors immortalized by transformation with a recombinant retroviral vector harboring a dominant-negative retinoic acid receptor (Tsai et al, 1994). Proliferation of these cells is dependent on SCF (see also: Factor-dependent cell lines).
capable of differentiation into erythroid cells, myeloid cells, and lymphoid cells and are thought to represent a reliable and authentic model of hematopoietic progenitor lineage commitment and differentiation (Du et al, 2002; Ma et al, 2002; Pawlak et al, 2000; Tsai et al, 1993). The EML C1
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