EHV-2 E1 orf
[Equine herpesvirus 2 open reading frame E1] EHV-2 is a gammaherpesvirus related to other lymphotropic herpesviruses such as herpesvirus saimiri and Epstein-Barr virus. The E1 open reading frame encodes a G-protein-coupled receptor homolog that shows 31 to 47 % amino acid identity with known receptors of CC-Chemokines. Eotaxin has been shown to act as a functional ligand for the virus-encoded receptor.
For other entries pertaining to cell death mechanisms see also the Apoptosis and Cell Death Dictionary section of this encyclopedia.
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Entry last modified: January 2002
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