ECGF-2a |
EC-GRAM |
HUSI-I |
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[Endothelial cell growth factor-2b] This factor is isolated from the serum-free medium (see also: SFM, conditioned medium) of hepatoma cells. It stimulates the growth of endothelial cells.
ECGF-2b is identical with the proteins known as Bikunin, urinary trypsin inhibitor and HI-30 (human inhibitor 30 kDa). These proteins are specific inhibitors of serine proteases. They are the biologically active components of the Inter-alpha-trypsin inhibitor complex (see: ITI).
Examination of the mRNA reveals that the complex is a fusion protein of HI-30 and
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