EBI-1-Ligand Chemokine |
EBI-6 |
CLIP peptide |
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[EBI-3(+), EBI-3(-)]
[EBV induced gene-3; Epstein-Barr virus induced gene 3] The EBI-3 cDNA encodes a secreted 34 kDa glycoprotein which lacks a membrane-anchoring motif. Despite the absence of a membrane-anchoring motif EBI-3 is present also on the plasma membrane of EBV-transformed B-lymphocytes and of transfected cells.
EBI-3 is a member of the hematopoietin receptor family (see also: Hematopoietins) related to the p40 subunit of IL12 and to the receptor for ciliary neurotrophic factor (see: CNTF). EBI-3 has been shown to be a component of other heterodimeric cytokines,
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