Ductular reaction cells

this term refers to a cell type residing in the vicinity of peribiliary glands and expanding in response to liver injury during a process usually referred to as ductular reaction that is associated with some type of reactive bile duct hyperplasia and involves cholangiocytes, hepatocytes, and hepatic progenitor cells (for overview see: Williams MJ et al, 2014; Sato K et al, 2019).

Wang N et al (2020) have reported that Ductular reaction cells are a type of intermediate stem cells with proliferative potential that can differentiate into hepatocytes and cholangiocytes and are involved in intrahepatic biliary regeneration. They have identified high levels of the stem cell marker LGR5 ... ... ... ...
 
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Entry last modified: May 2023