DWORF

[Dwarf open reading frame] the approved gene symbol is STRIT1 [Small transmembrane regulator of ion transport 1].

DWORF is a highly conserved peptide (MAEKAGSTFSHLLVPILLLIGWIVGCIIMIYVVFS), most likely encoded by a transcript classified as long non-coding RNA (Nelson et al, 2016). DWORF is expressed almost exclusively in cardiac ventricular muscle. Its expression gradually increases from postnatal development through to adulthood, and its expression is downregulated in hypertrophic and/or ischemic failing human and mouse ... ... ... ...
 
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Entry last modified: May 2021