DRAGON

[DRG11-responsive axonal guidance and outgrowth of neurite] DRAGON has been identified as a membrane-associated [glycosyl-phosphatidylinositol (GPI)-anchored] protein the expression of which is transcriptionally regulated by DRG11, a transcription factor expressed in embryonic dorsal root ganglion and dorsal horn neurons that has a role in the development of sensory circuits.

DRAGON shares high sequence homology with two other GPI-anchored membrane proteins known as RGM [repulsive guidance molecule] and is known also as RGMb [repulsive guidance molecule B]. DRAGON and the related proteins are highly conserved among mammals, zebrafish, chicken, and ... ... ... ...
 
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Entry last modified: June 2010