Dms |
DMS 79 |
Tissue-derived growth inhibitor |
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This cell line with epithelial morphology has been established from a small cell carcinoma of the lung (SCLC) isolated from a 54 year-old male patient. The cells express the cell surface antigens Leu7, Class-1 HLA, Class-2 HLA and My23. The cells are tumorigenic in nude mice.
DMS 53 cells exhibit mature endocrine differentiation features and secrete a large variety of hormones into the conditioned medium, including 17-beta-estradiol, ACTH, bombesin, calcitonin (multiple species and unusually high amounts), chorionic gonadotrophin, glucagon,
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