Cytotoxicity stimulating factor-L3 |
Cytotoxic lymphocyte maturation factor |
Infectious spleen and kidney necrosis virus orf48R |
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abbr. KAF (a term with multiple meanings). This biochemically uncharacterized factor is an acidic protein of 70-100 kDa produced by some macrophage-like cell lines and the human monocytic leukemia cell line THP-1. It activates human cytotoxic killer T-lymphocytes in vitro against autologous tumors (Maeda et al, 1989).
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