CySCs |
CySF-L1 |
GPIc* |
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[cytotoxicity stimulating factor] This biochemically uncharacterized factor (approximately 10 kDa or less) has been isolated from dialysable human extract as three different species, designated CySF-L1, CySF-L2, and CySF-L3 (Doelker and Anderer, 1992; Neidlinger and Anderer, 1991).
The three CySF activities function as a cytotoxicity stimulating factor and activate natural killer cytotoxicity against tumor cells (K562; DAUDI; Raji; MOLT4; sensitive or resistant to NK-cells) when preincubated with effector cells for 72 hrs.
CySF-L2 is capable also of activating
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