cTregs |
CTRP1 |
QGKRPWIL |
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This antimicrobial peptide, PFLWGLIPGAISAVTSLIKK, isolated from the venom of the scorpion Chaerilus tricostatus shows potent growth-inhibitory activity against standard Gram-positive bacteria and Candida albicans at low concentrations. Ctriporin is able to inhibit antibiotic-resistant pathogens, including MRSA, methicillin-resistant coagulase-negative Staphylococcus (MRCNS), and penicillin-resistant Staphylococcus epidermidis strains. Ctriporin ointment application to mouse skin shows reasonable antibacterial activity in vivo.
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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