catesbeianalectin |
Cateslytin |
type VI neuregulin-1 |
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Catesbeianin-1, MMRVMRRKTKVIWEKKDFIGLYSID, isolated from the skin of Lithobates catesbeianus (American bullfrog) has antimicrobial activity against Gram-positive bacteria and Gram-negative bacteria. Catesbeianin-1 significantly inhibits the growth of methicillin-resistant Staphylococcus aureus at 3.1 µg/mL. The peptide shows moderate hemolytic activity. The LD50 of catesbeianin-1 in mice is 80 mg/kg (Xu et al, 2017).
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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