Cyritestin 2 |
cyrostatin |
clump cells |
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[cytokine receptor-like protein] The CYRL cDNA shows significant homology to the IL3 receptor-alpha and has been cloned from a rat brain cDNA. The authors have stated that the extracellular domain is too divergent from the mouse IL3R-alpha sequence to suggest that CYRL is the rat ortholog of IL3R-alpha.
High level of CYRL mRNA are found in the testis. The gene is expressed also in the lung, spleen, brain, and heart.
The function of this receptor and its ligands are not known.
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