CRN-6 |
CRO-AP/2 |
Glu-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe |
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[cysteine-rich neurotrophic factor] This protein of 13.1 kDa was purified from the mollusk Lymnaea stagnalis on the basis of its ability to bind to the p75 neurotrophin receptor (p75NTR) with nanomolar affinity. CRNF does not display sequence similarities with neurotrophins or any other known gene products. CRNF evokes neurite outgrowth and modulates calcium currents in pedal motor neurons.
See also: Aplysia cysteine-rich neurotrophic factor.
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