ClpB |
CLP-2 cells |
Succinyl-CoA synthetase-alpha |
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[CLP cell]
[common lymphoid progenitor cells]; abbr. also simply CLPs. Kondo et al (1997) have reported that a population of hematopoietic cells from adult mouse bone marrow with the marker spectrum Lin(-), IL7 receptor positive, Thy1.1(-), Sca-1(low), and Kit(low), shows restricted development into T-cells, B-cells, and natural killer cells. This cell type has reconstitution capacity in vivo but cannot develop into myeloid cells in vivo or in vitro. These cells thus are common lymphoid progenitors in sites of early hematopoiesis
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