CATF |
Cathelicidin |
PVS |
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[cathelicidin B1] This chicken protein (PIRNWWIRIWEWLNGIRKRLRQRSPFYVRGHLNVTSTPQP) belongs to the group of avian cathelicidins (Goitsuka et al, 2007). The protein is produced by mucosal M cells exclusively in the epithelium of the bursa of Fabricius. The carboxyl-terminal peptide of chicken CATH-B1 has broad antimicrobial activity against Gram-positive bacteria and Gram-negative bacteria. Chicken CATH-B1 expression is restricted to the secretory epithelial cell neighbors of the M cells (secretory enterocytes), whereas its mature peptide
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