Boc-AEVD-CHO |
Boc-aspartyl(OMe)-fluoromethylketone |
Spheniscin-1 |
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[Boc-Asp(OMe)-fluoromethyl ketone; Boc-aspartyl(OMe)-fluoromethylketone; benzyloxycarbonyl-Asp-(oMe)-fluoromethyl ketone; t-butoxy carbonyl-Asp-fluoromethylketone] abbr. Boc-D, BD-fmk, Boc-D-fmk. In some articles the term BAF has been used.
Boc-aspartyl-fmk is a cell-permeable compound, a truncated form of the synthetic tripeptide VAD (Val-Ala-Asp) and considered a broad spectrum peptide caspase inhibitor. Sarin et al (1996) have reported that Boc-aspartyl-fmk blocks CPP32 like proteases but not ICE [
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