BSC-1 cell growth inhibitor
This inhibitor was isolated initially from conditioned medium of the established African Green Monkey kidney cell line, BSC-1 (Holley et al, 1985, 1987). The gene has been cloned by Hanks et al (1998), who have proposed the name Polyergin.
The BSC-1 cell growth inhibitor, TGF-beta-2 (see: TGF-beta) from human platelets, and CIF-B (Cartilage inducing factor B) are related, with only 32 amino acid exchanges out of 112 amino acids observed for the inhibitor and TGF-beta-2 (McPherson et al, 1989; Tucker et al, 1984).
The BSC-1 cell growth inhibitor and TGF-beta-2
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