BDGF-1.7 |
BDGF-A |
Müllerian inhibiting substance |
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[Bone-derived growth factor-2] This factor of 11.6 kDa was isolated initially from bone material (see also: BDGF) and found to induce collagen synthesis and DNA synthesis in bone cells. The factor is synthesized by osteoblasts and its production is enhanced by IFN-gamma (Canalis et al, 1980, 1986, 1987; Canalis and Centrella, 1986; Evans et al, 1991). Kato et al (1982) have shown that the protein acts on chondrocytes.
The factor is identical with the plasma protein Beta-2-Microglobulin (Canalis et al, 1987).
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