BCL2-like molecule short |
BCL2 regulated pathway |
Beta-END |
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abbr. BMF (a term with multiple meanings). BMF is the approved gene symbol. The murine gene has been isolated from a mouse embryo cDNA library by Puthalakath et al (2001). Human and mouse proteins are 87 % identical. The proteins contain a single BH3 domain (see also: BH3-only proteins).
Puthalakath et al (2001) have shown that BCL2 modifying factor interacts with rhe myosin V motor complex. BCL2 modifying factor is released by loss of cell attachment (see also: anoikis), and the protein can then bind to survival-promoting members of the BCL2
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